Dihexa vs Sermorelin

Side-by-side comparison of peptide medications.

FeatureDihexaSermorelin
Categorycognitivegrowth-hormone
AdministrationOral or transdermalSubcutaneous injection
Prescription RequiredYesYes

Dihexa

A small molecule peptidomimetic derived from angiotensin IV that potently activates the HGF/Met signaling system. Animal studies show cognitive enhancement orders of magnitude more potent than BDNF. Studied for Alzheimer's disease and cognitive decline.

Common uses: Cognitive enhancement, Memory improvement, Neuroprotection, Alzheimer's research

Sermorelin

A growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce and secrete growth hormone naturally. Often used as a gentler alternative to direct HGH therapy.

Common uses: Growth hormone optimization, Improved sleep, Body composition, Anti-aging