Ipamorelin vs Sermorelin
Side-by-side comparison of peptide medications.
| Feature | Ipamorelin | Sermorelin |
|---|---|---|
| Category | growth-hormone | growth-hormone |
| Administration | Subcutaneous injection | Subcutaneous injection |
| Prescription Required | Yes | Yes |
Ipamorelin
A selective growth hormone secretagogue receptor (GHSR) agonist that stimulates pulsatile growth hormone release without significantly raising cortisol, prolactin, or appetite. Considered one of the safest GH-releasing peptides.
Common uses: Growth hormone optimization, Anti-aging, Lean muscle support, Fat loss, Improved sleep
Sermorelin
A growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce and secrete growth hormone naturally. Often used as a gentler alternative to direct HGH therapy.
Common uses: Growth hormone optimization, Improved sleep, Body composition, Anti-aging