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Best MK-677 Telehealth Providers for Muscle growth and athletic performance

An oral growth hormone secretagogue that mimics the action of ghrelin, stimulating growth hormone release from the pituitary gland. Unlike injectable peptides, MK-677 is taken orally and has a long half-life.

Sarah Chen
Sarah ChenLead Health Editor
Dr. James Okafor, PharmDReviewed by Dr. James Okafor, PharmDPharmD
Updated January 15, 2025
Fact CheckedClinically Reviewed
Updated January 2025 — may be outdated
Growth hormoneOral capsulePrescription Required

What is MK-677 Used For?

  • Growth hormone elevation
  • Improved sleep quality
  • Increased lean mass
  • Bone density support

How MK-677 Works

MK-677 (Ibutamoren) is an orally active, non-peptide growth hormone secretagogue that mimics ghrelin by binding the ghrelin receptor (GHSR) in the hypothalamus and pituitary. This triggers a robust, sustained elevation in GH and downstream IGF-1 levels. Unlike injectable GH secretagogues, MK-677 is active for 24 hours after a single oral dose, making it uniquely convenient. It significantly increases GH pulse amplitude and frequency without suppressing the body's feedback loop.

What to Expect

Dramatically improved deep sleep and vivid dreams are typically reported within the first 1–2 weeks and are among the most consistent benefits. Increased appetite and water retention are also noticed early. Body composition improvements (lean mass gain, gradual fat loss) become apparent at 8–12 weeks. Clinical studies show sustained IGF-1 increases of 30–90% from baseline over 12-month use.

Common Side Effects

  • Increased appetite (can be pronounced)
  • Water retention and mild bloating
  • Fatigue or lethargy (especially during daytime dosing)
  • Mild blood glucose elevation (IGF-1 can reduce insulin sensitivity)
  • Tingling or numbness in extremities (carpal tunnel-like)
  • Vivid dreams (usually not unpleasant)

This is not a complete list of side effects. Always consult your prescribing physician before starting MK-677.

Frequently Asked Questions About MK-677

Is MK-677 a SARM?

No. MK-677 is often grouped with SARMs but is technically a growth hormone secretagogue — it has no affinity for androgen receptors and does not have androgenic effects. It works exclusively through the ghrelin/GH axis. It is not a controlled substance in the US, though it is prohibited by WADA.

When should MK-677 be taken?

Most protocols use MK-677 before bed to leverage the increase in appetite (minimized during sleep), maximize the nocturnal GH pulse it amplifies, and benefit from improved deep sleep. Some users split the dose, taking half at night and half in the morning, to manage appetite more evenly.

How long can MK-677 be used?

Clinical trials have studied MK-677 for up to 24 months continuously. Most telehealth protocols run 3–6 months, followed by labs (IGF-1, fasting glucose, HbA1c) and a break. Long-term use requires monitoring of blood glucose, as sustained IGF-1 elevation can modestly impair insulin sensitivity.

Does MK-677 suppress testosterone?

No. MK-677 works through the GH/IGF-1 axis and has no effect on the HPG axis (hypothalamic-pituitary-gonadal axis) that controls testosterone production. It does not cause hormonal suppression and does not require post-cycle therapy (PCT).

6 Providers Offering MK-677

Sorted by lowest price first.

ProviderPriceDoseRatingConsultationLab Testing
Amino Asylum

United States

$50/one-time60 capsules3.8/5Async TelehealthNot included
Defy Medical

Tampa, FL

$120/monthly25mg/day oral4.1/5Video TelehealthIncluded
Hone Health

Pittsburgh, PA

$149/monthly25mg/day oral4/5Async TelehealthIncluded
Maximus

Los Angeles, CA

$149/monthly25mg/day oral4/5Video TelehealthIncluded
Evolve Telemed

San Diego, CA

$150/monthly25mg/day oral4/5Video TelehealthIncluded
TruLife Health

Scottsdale, AZ

$180/monthly25mg/day oral4.1/5Video TelehealthIncluded

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