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Direct Meds vs Shed

A detailed head-to-head comparison of Direct Meds and Shed — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting Price$179/mo
Peptides2
ConsultationAsync Telehealth
Lab TestingNo
Shipping5-7 business days

Pros

  • Sublingual drop option — no injections required
  • Multiple medication formats (injectable + drops)
  • Competitive pricing on sublingual options
  • Both semaglutide and tirzepatide available

Cons

  • Compounded medications only — not FDA-approved
  • No insurance accepted
  • Limited clinical support beyond prescribing
  • Injectable pricing higher than some competitors
  • Relatively new with limited reviews
RatingNo reviews
Starting Price$175/mo
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Can coordinate GLP-1 with TRT under one provider
  • Video consultations available, not just async messaging
  • Straightforward single-price billing with no separate membership fees
  • Men's health specialization means providers are familiar with hormonal interactions that affect weight
  • HSA/FSA eligible

Cons

  • Men-only positioning may exclude patients who would otherwise benefit from the service
  • Available in only 42 states
  • No brand-name GLP-1 medications available
  • No dietitian access or dedicated weight loss coaching
  • Newer to weight management (expanded from TRT/ED in 2024)
  • Smaller patient base means less operational scale and potentially less refined processes

Pros & Cons

Peptide Pricing Comparison

PeptideDirect MedsShed
Semaglutide
$179/monthly
$297/monthly
$175/monthly
Tirzepatide
$224/monthly
$399/monthly
$325/monthly

Frequently Asked Questions

Is Direct Meds or Shed better?

Direct Meds offers 2 peptides and async telehealth consultations. Shed offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Direct Meds or Shed?

Direct Meds starts at $179/month while Shed starts at $175/month. However, pricing varies by peptide — see the pricing table above for a full breakdown.