Direct Meds vs Yucca Health
A detailed head-to-head comparison of Direct Meds and Yucca Health — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting Price$179/mo
Peptides2
ConsultationAsync Telehealth
Lab TestingNo
Shipping5-7 business days
Pros
- Sublingual drop option — no injections required
- Multiple medication formats (injectable + drops)
- Competitive pricing on sublingual options
- Both semaglutide and tirzepatide available
Cons
- Compounded medications only — not FDA-approved
- No insurance accepted
- Limited clinical support beyond prescribing
- Injectable pricing higher than some competitors
- Relatively new with limited reviews
RatingNo reviews
Starting Price$100/mo
Peptides4
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- 934 Trustpilot reviews at 4.6/5
- UPS 2-Day Air expedited shipping on all plans, standard (not an upgrade)
- Onboarding call included post-approval
- First-month $100 discount for new patients
- Buy-now-pay-later available on 6-month plans (Klarna, Affirm, Afterpay)
- 24/7 patient support
Cons
- Mid-to-high pricing: $275/mo (semaglutide monthly), $385/mo (tirzepatide monthly)
- Auto-subscription with renewal
- No refunds once medication has shipped
- No insurance billing
- HSA/FSA documentation (itemized receipts, letters of medical necessity) not provided
- No brand-name GLP-1 options
Pros & Cons
Peptide Pricing Comparison
| Peptide | Direct Meds | Yucca Health |
|---|---|---|
| NAD+ | Not offered | Price unavailable |
| Semaglutide | $179/monthly $297/monthly | $100/monthly $275/monthly $385/monthly |
| Sermorelin | Not offered | Price unavailable |
| Tirzepatide | $224/monthly $399/monthly | Price unavailable |
Frequently Asked Questions
Is Direct Meds or Yucca Health better?
Direct Meds offers 2 peptides and async telehealth consultations. Yucca Health offers 4 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Direct Meds or Yucca Health?
Direct Meds starts at $179/month while Yucca Health starts at $100/month. However, pricing varies by peptide — see the pricing table above for a full breakdown.