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Sequence vs Calibrate

A detailed head-to-head comparison of Sequence and Calibrate — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Founded by obesity medicine specialists
  • Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
  • Video consultations with experienced clinicians, not just questionnaire-based async reviews
  • Prior authorization and insurance appeals support included in membership
  • Personalized titration managed through follow-up video visits

Cons

  • Higher total cost for cash-pay patients
  • The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
  • No published independent outcomes data for their patient population
  • Insurance navigation success varies
  • Less established brand than Hims or Ro
Rating★★★★☆ 4.0/5
Starting Price$299/mo
Peptides3
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days

Pros

  • Comprehensive metabolic health program (not just medication)
  • Lab testing and metabolic panels included
  • Video consultations with obesity medicine specialists
  • Works with insurance to cover GLP-1 medication costs
  • Focus on sustainable weight loss and metabolic reset

Cons

  • Higher program cost ($299/mo for coaching + medication separate)
  • One-year commitment required
  • Insurance coverage for medication not guaranteed
  • Not available in all states

Pros & Cons

Peptide Pricing Comparison

PeptideSequenceCalibrate
LiraglutideNot offered
$299/monthly
SemaglutidePrice unavailable
$299/monthly
TirzepatidePrice unavailable
$299/monthly

Frequently Asked Questions

Is Sequence or Calibrate better?

Sequence offers 2 peptides and hybrid consultations. Calibrate offers 3 peptides with a 4/5 rating and video telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Sequence or Calibrate?

See the pricing table above for a detailed comparison.