How do Sesame and PlushCare compare on pricing?

Sesame starts at varying prices. PlushCare starts at varying prices. Actual cost depends on the medication, dose, and billing cycle you choose.

Sesame vs PlushCare

A detailed head-to-head comparison of Sesame and PlushCare — pricing, peptides, consultation models, and patient reviews.

At a Glance

	Sesame	PlushCare
Rating	No reviews	No reviews
Starting Price	N/A	N/A
Peptides Offered	2	2
Consultation	Async Telehealth	Hybrid
Lab Testing	Yes	No
Shipping	3-5 business days	3-5 business days
Headquarters	New York, NY	San Francisco, CA
Founded	2019	2014

Sesame

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationAsync Telehealth

Lab TestingYes

Shipping3-5 business days

Pros

No subscription, no membership required, no recurring charges
Lowest consultation cost in the market ($29-$79 per visit)
Full control over where you fill your prescription
Orforglipron and Wegovy HD available alongside other branded options
Broadest medication options
No long-term commitment

Cons

You handle medication sourcing, insurance navigation, and pharmacy selection yourself
No prior authorization assistance
No coaching, behavioral support, or structured program
No lab testing included or coordinated
Clinician quality varies across the marketplace (independent providers, not Sesame employees)
No ongoing care coordination between visits

PlushCare

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationHybrid

Lab TestingNo

Shipping3-5 business days

Pros

Backed by publicly traded Accolade
Insurance-based model
Video consultations with licensed physicians (not async questionnaire reviews)
Prescriptions filled at your own pharmacy
Can manage related health conditions in the same visit (primary care model)
Available in all 50 states

Cons

No compounded medications offered
Generalist physicians, not obesity medicine specialists
Low membership cost but consultation fees add up without insurance
Not focused on weight loss
No proprietary coaching, behavioral program, or weight-loss-specific support

Pros & Cons

Sesame

Pros

+No subscription, no membership required, no recurring charges
+Lowest consultation cost in the market ($29-$79 per visit)
+Full control over where you fill your prescription
+Orforglipron and Wegovy HD available alongside other branded options
+Broadest medication options
+No long-term commitment

Cons

-You handle medication sourcing, insurance navigation, and pharmacy selection yourself
-No prior authorization assistance
-No coaching, behavioral support, or structured program
-No lab testing included or coordinated
-Clinician quality varies across the marketplace (independent providers, not Sesame employees)
-No ongoing care coordination between visits

PlushCare

Pros

+Backed by publicly traded Accolade
+Insurance-based model
+Video consultations with licensed physicians (not async questionnaire reviews)
+Prescriptions filled at your own pharmacy
+Can manage related health conditions in the same visit (primary care model)
+Available in all 50 states

Cons

-No compounded medications offered
-Generalist physicians, not obesity medicine specialists
-Low membership cost but consultation fees add up without insurance
-Not focused on weight loss
-No proprietary coaching, behavioral program, or weight-loss-specific support

Peptide Pricing Comparison

Peptide	Sesame	PlushCare
Semaglutide	Price unavailable	Price unavailable
Tirzepatide	Price unavailable	Price unavailable

Frequently Asked Questions

Is Sesame or PlushCare better?

Sesame offers 2 peptides and async telehealth consultations. PlushCare offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Sesame or PlushCare?

See the pricing table above for a detailed comparison.

Learn More

Sesame

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PlushCare

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