DihexavsGHK-Cu
Dihexa vs GHK-Cu — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A small molecule peptidomimetic derived from angiotensin IV that potently activates the HGF/Met signaling system. Animal studies show cognitive enhancement orders of magnitude more potent than BDNF. Studied for Alzheimer's disease and cognitive decline.
A naturally occurring copper-binding peptide found in human plasma. Declines with age and is used therapeutically for skin rejuvenation, wound healing, and anti-inflammatory effects.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
Dihexa vs GHK-Cu: At a Glance
Full comparison across all key factors.
| Factor | Dihexa | GHK-CuALLY PICK |
|---|---|---|
| Category | cognitive | recovery |
| Also Known As | PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide | Copper Peptide, Glycyl-L-histidyl-L-lysine |
| Administration | Oral or transdermal | Topical or subcutaneous injection |
| Prescription | Required | Required |
| Providers | 3 providers | 4 providers✓ Better |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
3 providers offer both Dihexa and GHK-Cu.
| Provider | Dihexa | GHK-Cu | Consultation | Lab Testing |
|---|---|---|---|---|
 | $60/one-time | $35/one-time | Async Telehealth | No |
 | $200/monthly | $145/monthly | Video Telehealth | Yes |
 | $260/monthly | $195/monthly | Video Telehealth | Yes |
 | Not offered | $160/monthly | Video Telehealth | Yes |
Key Differences
Dihexa
A small molecule peptidomimetic derived from angiotensin IV that potently activates the HGF/Met signaling system. Animal studies show cognitive enhancement orders of magnitude more potent than BDNF. Studied for Alzheimer's disease and cognitive decline.
GHK-Cu
More ProvidersA naturally occurring copper-binding peptide found in human plasma. Declines with age and is used therapeutically for skin rejuvenation, wound healing, and anti-inflammatory effects.
Which Is Right for You?
Choose Dihexaif…
- You want a cognitive medication
- You prefer oral or transdermal administration
- 3 providers available on our platform
- Your primary goal is cognitive enhancement
- Your primary goal is memory improvement
Choose GHK-Cuif…
- You want a recovery medication
- You prefer topical or subcutaneous injection administration
- You want more provider options (4 available)
- Your primary goal is skin rejuvenation
- Your primary goal is wound healing
Frequently Asked Questions
What is the difference between Dihexa and GHK-Cu?
Which is cheaper, Dihexa or GHK-Cu?
Can I switch from Dihexa to GHK-Cu?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.