DihexavsLL-37
Dihexa vs LL-37 — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A small molecule peptidomimetic derived from angiotensin IV that potently activates the HGF/Met signaling system. Animal studies show cognitive enhancement orders of magnitude more potent than BDNF. Studied for Alzheimer's disease and cognitive decline.
The only known human cathelicidin antimicrobial peptide, naturally produced by immune cells and epithelial tissues. LL-37 has broad-spectrum antimicrobial activity alongside potent immunomodulatory and wound-healing properties.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
Dihexa vs LL-37: At a Glance
Full comparison across all key factors.
| Factor | Dihexa | LL-37 |
|---|---|---|
| Category | cognitive | recovery |
| Also Known As | PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide | Cathelicidin, hCAP18/LL-37 |
| Administration | Oral or transdermal | Topical or subcutaneous injection |
| Prescription | Required | Required |
| Providers | 3 providers | 3 providers |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
3 providers offer both Dihexa and LL-37.
| Provider | Dihexa | LL-37 | Consultation | Lab Testing |
|---|---|---|---|---|
 | $60/one-time | $50/one-time | Async Telehealth | No |
 | $200/monthly | $180/monthly | Video Telehealth | Yes |
 | $260/monthly | $240/monthly | Video Telehealth | Yes |
Key Differences
Dihexa
A small molecule peptidomimetic derived from angiotensin IV that potently activates the HGF/Met signaling system. Animal studies show cognitive enhancement orders of magnitude more potent than BDNF. Studied for Alzheimer's disease and cognitive decline.
LL-37
The only known human cathelicidin antimicrobial peptide, naturally produced by immune cells and epithelial tissues. LL-37 has broad-spectrum antimicrobial activity alongside potent immunomodulatory and wound-healing properties.
Which Is Right for You?
Choose Dihexaif…
- You want a cognitive medication
- You prefer oral or transdermal administration
- 3 providers available on our platform
- Your primary goal is cognitive enhancement
- Your primary goal is memory improvement
Choose LL-37if…
- You want a recovery medication
- You prefer topical or subcutaneous injection administration
- 3 providers available on our platform
- Your primary goal is antimicrobial defense
- Your primary goal is chronic wound healing
Frequently Asked Questions
What is the difference between Dihexa and LL-37?
Which is cheaper, Dihexa or LL-37?
Can I switch from Dihexa to LL-37?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.