IGF-1 LR3vsKisspeptin
IGF-1 LR3 vs Kisspeptin — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
A hypothalamic neuropeptide that acts as the primary regulator of the reproductive endocrine axis, triggering GnRH release and downstream LH/FSH production. Used to evaluate and treat disorders of sexual function and fertility in both men and women.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
IGF-1 LR3 vs Kisspeptin: At a Glance
Full comparison across all key factors.
| Factor | IGF-1 LR3 | Kisspeptin |
|---|---|---|
| Category | growth-hormone | sexual-health |
| Also Known As | Insulin-like Growth Factor-1 Long R3, Long R3 IGF-1 | Metastin, KP-10, KP-54 |
| Administration | Subcutaneous or intramuscular injection | Subcutaneous injection |
| Prescription | Required | Required |
| Providers | 3 providers | 3 providers |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
2 providers offer both IGF-1 LR3 and Kisspeptin.
| Provider | IGF-1 LR3 | Kisspeptin | Consultation | Lab Testing |
|---|---|---|---|---|
 | $250/monthly | $200/monthly | Video Telehealth | Yes |
 | $320/monthly | $260/monthly | Video Telehealth | Yes |
 | $55/one-time | Not offered | Async Telehealth | No |
 | Not offered | $220/monthly | Video Telehealth | Yes |
Key Differences
IGF-1 LR3
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
Kisspeptin
A hypothalamic neuropeptide that acts as the primary regulator of the reproductive endocrine axis, triggering GnRH release and downstream LH/FSH production. Used to evaluate and treat disorders of sexual function and fertility in both men and women.
Which Is Right for You?
Choose IGF-1 LR3if…
- You want a growth-hormone medication
- You prefer subcutaneous or intramuscular injection administration
- 3 providers available on our platform
- Your primary goal is muscle hypertrophy
- Your primary goal is fat loss
Choose Kisspeptinif…
- You want a sexual-health medication
- You prefer subcutaneous injection administration
- 3 providers available on our platform
- Your primary goal is low libido
- Your primary goal is hormonal balance
Frequently Asked Questions
What is the difference between IGF-1 LR3 and Kisspeptin?
Which is cheaper, IGF-1 LR3 or Kisspeptin?
Can I switch from IGF-1 LR3 to Kisspeptin?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.