IGF-1 LR3vsKPV
IGF-1 LR3 vs KPV — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
A tripeptide fragment derived from the C-terminus of alpha-melanocyte-stimulating hormone (α-MSH). KPV carries the anti-inflammatory properties of α-MSH without its melanogenic effects, making it a targeted tool for gut and systemic inflammation.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
IGF-1 LR3 vs KPV: At a Glance
Full comparison across all key factors.
| Factor | IGF-1 LR3 | KPV |
|---|---|---|
| Category | growth-hormone | recovery |
| Also Known As | Insulin-like Growth Factor-1 Long R3, Long R3 IGF-1 | Lys-Pro-Val, Alpha-MSH tripeptide |
| Administration | Subcutaneous or intramuscular injection | Oral capsule or subcutaneous injection |
| Prescription | Required | Required |
| Providers | 3 providers | 3 providers |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
2 providers offer both IGF-1 LR3 and KPV.
| Provider | IGF-1 LR3 | KPV | Consultation | Lab Testing |
|---|---|---|---|---|
 | $250/monthly | $130/monthly | Video Telehealth | Yes |
 | $320/monthly | $170/monthly | Video Telehealth | Yes |
 | $55/one-time | Not offered | Async Telehealth | No |
 | Not offered | $145/monthly | Video Telehealth | Yes |
Key Differences
IGF-1 LR3
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
KPV
A tripeptide fragment derived from the C-terminus of alpha-melanocyte-stimulating hormone (α-MSH). KPV carries the anti-inflammatory properties of α-MSH without its melanogenic effects, making it a targeted tool for gut and systemic inflammation.
Which Is Right for You?
Choose IGF-1 LR3if…
- You want a growth-hormone medication
- You prefer subcutaneous or intramuscular injection administration
- 3 providers available on our platform
- Your primary goal is muscle hypertrophy
- Your primary goal is fat loss
Choose KPVif…
- You want a recovery medication
- You prefer oral capsule or subcutaneous injection administration
- 3 providers available on our platform
- Your primary goal is gut inflammation
- Your primary goal is ibd and crohn's support
Frequently Asked Questions
What is the difference between IGF-1 LR3 and KPV?
Which is cheaper, IGF-1 LR3 or KPV?
Can I switch from IGF-1 LR3 to KPV?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.