IGF-1 LR3vsNAD+
IGF-1 LR3 vs NAD+ — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
A coenzyme found in every living cell, critical for energy metabolism and cellular repair. Levels decline with age, and supplementation is used to support longevity and cognitive function.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
IGF-1 LR3 vs NAD+: At a Glance
Full comparison across all key factors.
| Factor | IGF-1 LR3 | NAD+ALLY PICK |
|---|---|---|
| Category | growth-hormone | anti-aging |
| Also Known As | Insulin-like Growth Factor-1 Long R3, Long R3 IGF-1 | Nicotinamide adenine dinucleotide |
| Administration | Subcutaneous or intramuscular injection | Subcutaneous injection or IV infusion |
| Prescription | Required | Required |
| Providers | 3 providers | 10 providers✓ Better |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
2 providers offer both IGF-1 LR3 and NAD+.
| Provider | IGF-1 LR3 | NAD+ | Consultation | Lab Testing |
|---|---|---|---|---|
 | $250/monthly | $220/monthly | Video Telehealth | Yes |
 | $320/monthly | $300/monthly | Video Telehealth | Yes |
| Not offered | Price unavailable | Hybrid | No | |
| Not offered | Price unavailable | Async Telehealth | No | |
 | $55/one-time | Not offered | Async Telehealth | No |
| Not offered | Price unavailable | Async Telehealth | No | |
| Not offered | Price unavailable | Hybrid | No | |
| Not offered | Price unavailable | Async Telehealth | No | |
| Not offered | Price unavailable | Hybrid | No | |
| Not offered | Price unavailable | Hybrid | No | |
| Not offered | Price unavailable | Hybrid | No |
Key Differences
IGF-1 LR3
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
NAD+
More ProvidersA coenzyme found in every living cell, critical for energy metabolism and cellular repair. Levels decline with age, and supplementation is used to support longevity and cognitive function.
Which Is Right for You?
Choose IGF-1 LR3if…
- You want a growth-hormone medication
- You prefer subcutaneous or intramuscular injection administration
- 3 providers available on our platform
- Your primary goal is muscle hypertrophy
- Your primary goal is fat loss
Choose NAD+if…
- You want a anti-aging medication
- You prefer subcutaneous injection or iv infusion administration
- You want more provider options (10 available)
- Your primary goal is anti-aging
- Your primary goal is energy and focus
Frequently Asked Questions
What is the difference between IGF-1 LR3 and NAD+?
Which is cheaper, IGF-1 LR3 or NAD+?
Can I switch from IGF-1 LR3 to NAD+?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.