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AOD-9604vsMOTS-c

AOD-9604 vs MOTS-c — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.

Ally VerdictAOD-9604 has broader provider availability

Quick Verdict

Based on clinical evidence and real patient data

AOD-9604Ally Pick

A modified fragment (amino acids 176-191) of human growth hormone designed to stimulate fat metabolism without the growth-promoting effects of full HGH. Studied as a targeted fat-loss peptide.

Providers: 4Route: Subcutaneous injection

A mitochondria-derived peptide encoded within the mitochondrial genome. MOTS-c regulates metabolic homeostasis, enhances insulin sensitivity, and has shown promise in extending healthspan in animal studies. Levels naturally decline with age.

Providers: 2Route: Subcutaneous injection

Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.

AOD-9604 vs MOTS-c: At a Glance

Full comparison across all key factors.

FactorAOD-9604ALLY PICKMOTS-c
Categoryweight-lossanti-aging
Also Known AsAnti-Obesity Drug 9604Mitochondrial Open Reading Frame of the 12S rRNA-c
AdministrationSubcutaneous injectionSubcutaneous injection
PrescriptionRequiredRequired
Providers4 providers✓ Better2 providers
Common Uses
  • Fat metabolism
  • Body composition
  • Weight management
  • Metabolic health
  • Insulin sensitivity
  • Longevity
  • Exercise performance

Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.

Pricing by Provider

2 providers offer both AOD-9604 and MOTS-c.

ProviderAOD-9604MOTS-cConsultationLab Testing
Defy Medical logo
Defy Medical
$160/monthly$220/monthlyVideo TelehealthYes
TruLife Health logo
TruLife Health
$220/monthly$280/monthlyVideo TelehealthYes
Evolve Telemed logo
Evolve Telemed
$185/monthlyNot offeredVideo TelehealthYes
Heally logo
Heally
$150/monthlyNot offeredVideo TelehealthNo

Key Differences

AOD-9604

More Providers

A modified fragment (amino acids 176-191) of human growth hormone designed to stimulate fat metabolism without the growth-promoting effects of full HGH. Studied as a targeted fat-loss peptide.

Category: weight-loss
Route: Subcutaneous injection
Uses: Fat metabolism, Body composition

MOTS-c

A mitochondria-derived peptide encoded within the mitochondrial genome. MOTS-c regulates metabolic homeostasis, enhances insulin sensitivity, and has shown promise in extending healthspan in animal studies. Levels naturally decline with age.

Category: anti-aging
Route: Subcutaneous injection
Uses: Metabolic health, Insulin sensitivity

Which Is Right for You?

Choose AOD-9604if…

  • You want a weight-loss medication
  • You prefer subcutaneous injection administration
  • You want more provider options (4 available)
  • Your primary goal is fat metabolism
  • Your primary goal is body composition

Choose MOTS-cif…

  • You want a anti-aging medication
  • You prefer subcutaneous injection administration
  • 2 providers available on our platform
  • Your primary goal is metabolic health
  • Your primary goal is insulin sensitivity

Frequently Asked Questions

What is the difference between AOD-9604 and MOTS-c?
AOD-9604 is a weight-loss peptide primarily used for fat metabolism and body composition. MOTS-c is a anti-aging peptide primarily used for metabolic health and insulin sensitivity. Both are administered via subcutaneous injection.
Which is cheaper, AOD-9604 or MOTS-c?
Pricing varies by provider. AOD-9604 is available from 4 providers and MOTS-c from 2 providers. Use the pricing table above to compare costs across all providers.
Can I switch from AOD-9604 to MOTS-c?
Switching between medications should always be done under medical supervision. Consult with your healthcare provider before making any changes to your treatment plan. 2 providers on our platform offer both medications.

Medical Disclaimer

This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.

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