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EpithalonvsTB-500

Epithalon vs TB-500 — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.

Ally VerdictTB-500 has broader provider availability

Quick Verdict

Based on clinical evidence and real patient data

A synthetic tetrapeptide studied for its ability to activate telomerase, the enzyme responsible for maintaining telomere length. Research suggests potential anti-aging effects at the cellular level.

Providers: 3Route: Subcutaneous injection
TB-500Ally Pick

A synthetic fragment of thymosin beta-4, a naturally occurring peptide involved in tissue repair and regeneration. Studied for its ability to promote healing of muscles, tendons, ligaments, and skin.

Providers: 6Route: Subcutaneous injection

Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.

Epithalon vs TB-500: At a Glance

Full comparison across all key factors.

FactorEpithalonTB-500ALLY PICK
Categoryanti-agingrecovery
Also Known AsEpitalon, EpithalaminThymosin Beta-4 Fragment
AdministrationSubcutaneous injectionSubcutaneous injection
PrescriptionRequiredRequired
Providers3 providers6 providers✓ Better
Common Uses
  • Telomere maintenance
  • Anti-aging
  • Sleep cycle regulation
  • Cellular longevity
  • Muscle repair
  • Tendon healing
  • Reduced inflammation
  • Wound recovery

Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.

Pricing by Provider

3 providers offer both Epithalon and TB-500.

ProviderEpithalonTB-500ConsultationLab Testing
Amino Asylum logo
Amino Asylum
$55/one-time$40/one-timeAsync TelehealthNo
Defy Medical logo
Defy Medical
$250/per-cycle$180/monthlyVideo TelehealthYes
TruLife Health logo
TruLife Health
$320/per-cycle$240/monthlyVideo TelehealthYes
Evolve Telemed logo
Evolve Telemed
Not offered$195/monthlyVideo TelehealthYes
Heally logo
Heally
Not offered$165/monthlyVideo TelehealthNo
Maximus logo
Maximus
Not offered$199/monthlyVideo TelehealthYes

Key Differences

Epithalon

A synthetic tetrapeptide studied for its ability to activate telomerase, the enzyme responsible for maintaining telomere length. Research suggests potential anti-aging effects at the cellular level.

Category: anti-aging
Route: Subcutaneous injection
Uses: Telomere maintenance, Anti-aging

TB-500

More Providers

A synthetic fragment of thymosin beta-4, a naturally occurring peptide involved in tissue repair and regeneration. Studied for its ability to promote healing of muscles, tendons, ligaments, and skin.

Category: recovery
Route: Subcutaneous injection
Uses: Muscle repair, Tendon healing

Which Is Right for You?

Choose Epithalonif…

  • You want a anti-aging medication
  • You prefer subcutaneous injection administration
  • 3 providers available on our platform
  • Your primary goal is telomere maintenance
  • Your primary goal is anti-aging

Choose TB-500if…

  • You want a recovery medication
  • You prefer subcutaneous injection administration
  • You want more provider options (6 available)
  • Your primary goal is muscle repair
  • Your primary goal is tendon healing

Frequently Asked Questions

What is the difference between Epithalon and TB-500?
Epithalon is a anti-aging peptide primarily used for telomere maintenance and anti-aging. TB-500 is a recovery peptide primarily used for muscle repair and tendon healing. Both are administered via subcutaneous injection.
Which is cheaper, Epithalon or TB-500?
Pricing varies by provider. Epithalon is available from 3 providers and TB-500 from 6 providers. Use the pricing table above to compare costs across all providers.
Can I switch from Epithalon to TB-500?
Switching between medications should always be done under medical supervision. Consult with your healthcare provider before making any changes to your treatment plan. 3 providers on our platform offer both medications.

Medical Disclaimer

This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.

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