GHK-CuvsIGF-1 LR3
GHK-Cu vs IGF-1 LR3 — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A naturally occurring copper-binding peptide found in human plasma. Declines with age and is used therapeutically for skin rejuvenation, wound healing, and anti-inflammatory effects.
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
GHK-Cu vs IGF-1 LR3: At a Glance
Full comparison across all key factors.
| Factor | GHK-CuALLY PICK | IGF-1 LR3 |
|---|---|---|
| Category | recovery | growth-hormone |
| Also Known As | Copper Peptide, Glycyl-L-histidyl-L-lysine | Insulin-like Growth Factor-1 Long R3, Long R3 IGF-1 |
| Administration | Topical or subcutaneous injection | Subcutaneous or intramuscular injection |
| Prescription | Required | Required |
| Providers | 4 providers✓ Better | 3 providers |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
3 providers offer both GHK-Cu and IGF-1 LR3.
| Provider | GHK-Cu | IGF-1 LR3 | Consultation | Lab Testing |
|---|---|---|---|---|
 | $35/one-time | $55/one-time | Async Telehealth | No |
 | $145/monthly | $250/monthly | Video Telehealth | Yes |
 | $195/monthly | $320/monthly | Video Telehealth | Yes |
 | $160/monthly | Not offered | Video Telehealth | Yes |
Key Differences
GHK-Cu
More ProvidersA naturally occurring copper-binding peptide found in human plasma. Declines with age and is used therapeutically for skin rejuvenation, wound healing, and anti-inflammatory effects.
IGF-1 LR3
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
Which Is Right for You?
Choose GHK-Cuif…
- You want a recovery medication
- You prefer topical or subcutaneous injection administration
- You want more provider options (4 available)
- Your primary goal is skin rejuvenation
- Your primary goal is wound healing
Choose IGF-1 LR3if…
- You want a growth-hormone medication
- You prefer subcutaneous or intramuscular injection administration
- 3 providers available on our platform
- Your primary goal is muscle hypertrophy
- Your primary goal is fat loss
Frequently Asked Questions
What is the difference between GHK-Cu and IGF-1 LR3?
Which is cheaper, GHK-Cu or IGF-1 LR3?
Can I switch from GHK-Cu to IGF-1 LR3?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.