IGF-1 LR3vsMelanotan II
IGF-1 LR3 vs Melanotan II — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
A synthetic melanocortin peptide analog that activates multiple melanocortin receptors. Originally studied for tanning, it also has effects on sexual arousal and appetite regulation.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
IGF-1 LR3 vs Melanotan II: At a Glance
Full comparison across all key factors.
| Factor | IGF-1 LR3 | Melanotan II |
|---|---|---|
| Category | growth-hormone | sexual-health |
| Also Known As | Insulin-like Growth Factor-1 Long R3, Long R3 IGF-1 | MT-2, MT-II |
| Administration | Subcutaneous or intramuscular injection | Subcutaneous injection |
| Prescription | Required | Required |
| Providers | 3 providers | 3 providers |
| Common Uses |
|
|
Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
2 providers offer both IGF-1 LR3 and Melanotan II.
| Provider | IGF-1 LR3 | Melanotan II | Consultation | Lab Testing |
|---|---|---|---|---|
 | $55/one-time | $30/one-time | Async Telehealth | No |
 | $250/monthly | $120/per-vial | Video Telehealth | Yes |
 | Not offered | $110/per-vial | Video Telehealth | No |
 | $320/monthly | Not offered | Video Telehealth | Yes |
Key Differences
IGF-1 LR3
A long-acting analog of insulin-like growth factor-1 (IGF-1) with an arginine substitution that reduces binding to IGF-binding proteins, extending its half-life. IGF-1 is the primary downstream mediator of growth hormone's anabolic effects.
Melanotan II
A synthetic melanocortin peptide analog that activates multiple melanocortin receptors. Originally studied for tanning, it also has effects on sexual arousal and appetite regulation.
Which Is Right for You?
Choose IGF-1 LR3if…
- You want a growth-hormone medication
- You prefer subcutaneous or intramuscular injection administration
- 3 providers available on our platform
- Your primary goal is muscle hypertrophy
- Your primary goal is fat loss
Choose Melanotan IIif…
- You want a sexual-health medication
- You prefer subcutaneous injection administration
- 3 providers available on our platform
- Your primary goal is sexual dysfunction
- Your primary goal is skin pigmentation
Frequently Asked Questions
What is the difference between IGF-1 LR3 and Melanotan II?
Which is cheaper, IGF-1 LR3 or Melanotan II?
Can I switch from IGF-1 LR3 to Melanotan II?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.