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Melanotan IIvsSS-31

Melanotan II vs SS-31 — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.

Ally VerdictMelanotan II has broader provider availability

Quick Verdict

Based on clinical evidence and real patient data

Melanotan IIAlly Pick

A synthetic melanocortin peptide analog that activates multiple melanocortin receptors. Originally studied for tanning, it also has effects on sexual arousal and appetite regulation.

Providers: 3Route: Subcutaneous injection

A mitochondria-targeting tetrapeptide that concentrates in the inner mitochondrial membrane, protecting cardiolipin from oxidative damage. Restores mitochondrial function in aged and metabolically stressed cells, with clinical trials in heart failure and Barth syndrome.

Providers: 2Route: Subcutaneous injection

Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.

Melanotan II vs SS-31: At a Glance

Full comparison across all key factors.

FactorMelanotan IIALLY PICKSS-31
Categorysexual-healthanti-aging
Also Known AsMT-2, MT-IIElamipretide, Bendavia, MTP-131
AdministrationSubcutaneous injectionSubcutaneous injection
PrescriptionRequiredRequired
Providers3 providers✓ Better2 providers
Common Uses
  • Sexual dysfunction
  • Skin pigmentation
  • Appetite regulation
  • Mitochondrial function
  • Cellular energy
  • Heart health
  • Age-related tissue decline

Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.

Pricing by Provider

1 provider offers both Melanotan II and SS-31.

ProviderMelanotan IISS-31ConsultationLab Testing
Defy Medical logo
Defy Medical
$120/per-vial$280/monthlyVideo TelehealthYes
Amino Asylum logo
Amino Asylum
$30/one-timeNot offeredAsync TelehealthNo
Heally logo
Heally
$110/per-vialNot offeredVideo TelehealthNo
TruLife Health logo
TruLife Health
Not offered$350/monthlyVideo TelehealthYes

Key Differences

Melanotan II

More Providers

A synthetic melanocortin peptide analog that activates multiple melanocortin receptors. Originally studied for tanning, it also has effects on sexual arousal and appetite regulation.

Category: sexual-health
Route: Subcutaneous injection
Uses: Sexual dysfunction, Skin pigmentation

SS-31

A mitochondria-targeting tetrapeptide that concentrates in the inner mitochondrial membrane, protecting cardiolipin from oxidative damage. Restores mitochondrial function in aged and metabolically stressed cells, with clinical trials in heart failure and Barth syndrome.

Category: anti-aging
Route: Subcutaneous injection
Uses: Mitochondrial function, Cellular energy

Which Is Right for You?

Choose Melanotan IIif…

  • You want a sexual-health medication
  • You prefer subcutaneous injection administration
  • You want more provider options (3 available)
  • Your primary goal is sexual dysfunction
  • Your primary goal is skin pigmentation

Choose SS-31if…

  • You want a anti-aging medication
  • You prefer subcutaneous injection administration
  • 2 providers available on our platform
  • Your primary goal is mitochondrial function
  • Your primary goal is cellular energy

Frequently Asked Questions

What is the difference between Melanotan II and SS-31?
Melanotan II is a sexual-health peptide primarily used for sexual dysfunction and skin pigmentation. SS-31 is a anti-aging peptide primarily used for mitochondrial function and cellular energy. Both are administered via subcutaneous injection.
Which is cheaper, Melanotan II or SS-31?
Pricing varies by provider. Melanotan II is available from 3 providers and SS-31 from 2 providers. Use the pricing table above to compare costs across all providers.
Can I switch from Melanotan II to SS-31?
Switching between medications should always be done under medical supervision. Consult with your healthcare provider before making any changes to your treatment plan. 1 provider on our platform offers both medications.

Medical Disclaimer

This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.

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