MK-677vsPT-141
MK-677 vs PT-141 — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
An oral growth hormone secretagogue that mimics the action of ghrelin, stimulating growth hormone release from the pituitary gland. Unlike injectable peptides, MK-677 is taken orally and has a long half-life.
A melanocortin receptor agonist that works through the central nervous system to improve sexual arousal. FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
MK-677 vs PT-141: At a Glance
Full comparison across all key factors.
| Factor | MK-677ALLY PICK | PT-141 |
|---|---|---|
| Category | growth-hormone | sexual-health |
| Also Known As | Ibutamoren | Bremelanotide, Vyleesi |
| Administration | Oral capsule | Subcutaneous injection |
| Prescription | Required | Required |
| Providers | 6 providers✓ Better | 5 providers |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
4 providers offer both MK-677 and PT-141.
| Provider | MK-677 | PT-141 | Consultation | Lab Testing |
|---|---|---|---|---|
 | $50/one-time | $30/one-time | Async Telehealth | No |
 | $120/monthly | $150/per-vial | Video Telehealth | Yes |
 | $150/monthly | $160/monthly | Video Telehealth | Yes |
 | $180/monthly | $200/monthly | Video Telehealth | Yes |
 | Not offered | $140/monthly | Video Telehealth | No |
 | $149/monthly | Not offered | Async Telehealth | Yes |
 | $149/monthly | Not offered | Video Telehealth | Yes |
Key Differences
MK-677
More ProvidersAn oral growth hormone secretagogue that mimics the action of ghrelin, stimulating growth hormone release from the pituitary gland. Unlike injectable peptides, MK-677 is taken orally and has a long half-life.
PT-141
A melanocortin receptor agonist that works through the central nervous system to improve sexual arousal. FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women.
Which Is Right for You?
Choose MK-677if…
- You want a growth-hormone medication
- You prefer oral capsule administration
- You want more provider options (6 available)
- Your primary goal is growth hormone elevation
- Your primary goal is improved sleep quality
Choose PT-141if…
- You want a sexual-health medication
- You prefer subcutaneous injection administration
- 5 providers available on our platform
- Your primary goal is sexual dysfunction
- Your primary goal is low libido
Frequently Asked Questions
What is the difference between MK-677 and PT-141?
Which is cheaper, MK-677 or PT-141?
Can I switch from MK-677 to PT-141?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.