LL-37vsSemax
LL-37 vs Semax — independent comparison of uses, administration, pricing across providers, and key differences. Last reviewed April 21, 2026.
Quick Verdict
Based on clinical evidence and real patient data
The only known human cathelicidin antimicrobial peptide, naturally produced by immune cells and epithelial tissues. LL-37 has broad-spectrum antimicrobial activity alongside potent immunomodulatory and wound-healing properties.
A synthetic peptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10. Developed in Russia for cognitive enhancement and neuroprotection, it modulates BDNF and serotonin levels.
Best choice depends on your insurance, budget, and treatment history.Take the quiz to get a personalized recommendation.
LL-37 vs Semax: At a Glance
Full comparison across all key factors.
| Factor | LL-37 | SemaxALLY PICK |
|---|---|---|
| Category | recovery | cognitive |
| Also Known As | Cathelicidin, hCAP18/LL-37 | ACTH 4-10 Analog |
| Administration | Topical or subcutaneous injection | Intranasal spray |
| Prescription | Required | Required |
| Providers | 3 providers | 4 providers✓ Better |
| Common Uses |
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Data sourced from FDA prescribing information and peer-reviewed clinical trials. Prices reflect telehealth platform costs as of April 21, 2026. See our methodology.
Pricing by Provider
3 providers offer both LL-37 and Semax.
| Provider | LL-37 | Semax | Consultation | Lab Testing |
|---|---|---|---|---|
 | $50/one-time | $45/one-time | Async Telehealth | No |
 | $180/monthly | $120/monthly | Video Telehealth | Yes |
 | $240/monthly | $160/monthly | Video Telehealth | Yes |
 | Not offered | $140/monthly | Video Telehealth | Yes |
Key Differences
LL-37
The only known human cathelicidin antimicrobial peptide, naturally produced by immune cells and epithelial tissues. LL-37 has broad-spectrum antimicrobial activity alongside potent immunomodulatory and wound-healing properties.
Semax
More ProvidersA synthetic peptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10. Developed in Russia for cognitive enhancement and neuroprotection, it modulates BDNF and serotonin levels.
Which Is Right for You?
Choose LL-37if…
- You want a recovery medication
- You prefer topical or subcutaneous injection administration
- 3 providers available on our platform
- Your primary goal is antimicrobial defense
- Your primary goal is chronic wound healing
Choose Semaxif…
- You want a cognitive medication
- You prefer intranasal spray administration
- You want more provider options (4 available)
- Your primary goal is cognitive enhancement
- Your primary goal is neuroprotection
Frequently Asked Questions
What is the difference between LL-37 and Semax?
Which is cheaper, LL-37 or Semax?
Can I switch from LL-37 to Semax?
Medical Disclaimer
This comparison is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary. The information presented reflects publicly available data and may not account for your specific health situation.